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API2/MALT1 fusion gene t(11;18) probe reagent
Product Code:R-0501320Ⅰ-01/R-0501320Ⅰ-02/R-0501320Ⅱ-01/R-0501320Ⅱ-02/R-0501320Ⅲ-01/R-0501320Ⅲ-02/R-0501320Ⅳ-01/R-0501320Ⅳ-02
Probe name:GSP MALT / GSP API2
Product Code:Type I (direct FISH method)/Type II (biotin-labeled indirect FISH method)/Type III (digoxigenin-labeled indirect FISH method)/Type IV (TSA-FISH method)
Registration Number:
Clinical Value

Mucosa-associated lymphoid tissue (MALT) lymphoma is a group of extranodal B-cell non-Hodgkin's lymphoma originating from mucosa-associated lymphoid tissue;


t(11; 18)(q21; q21) causes the fusion of apoptosis inhibitor-2 gene (API2 also known as BIRC3) on chromosome 11 and MALT1 gene on chromosome 18 to form the API2- MALT1 fusion gene, which is specific to MALT lymphoma chromosomal translocation. The generation of the translocation is associated with low-grade malignant gastric and lung MALT lymphomas.