5T/box(Ⅰ-01)10T/box(Ⅰ-02)5T/box(Ⅱ-01)10T/box(Ⅱ-02)5T/box(Ⅲ-01)10T/box(Ⅲ-02)5T/box(Ⅳ-01)10T/box (IV-02)

5T/box(Ⅰ-01)10T/box(Ⅰ-02)5T/box(Ⅱ-01)10T/box(Ⅱ-02)5T/box(Ⅲ-01)10T/box(Ⅲ-02)5T/box(Ⅳ-01)10T/box (IV-02)
Pure or heterozygous deletion of 13q14 (DLEU1 gene) is the most common abnormality in CLL (more than 60% of cases); occurs in 16-40% of MM; poor prognosis;
DLEU gene deletion is also seen in lymphoma/myeloma/prostate cancer/head and neck cancer/non-small cell lung cancer and other tumors.